TY - BOOK AU - Silverman,Richard B. AU - Holladay,Mark W. TI - The organic chemistry of drug design and drug action SN - 9780123820303 U1 - 615.19 23 PY - 2014///] CY - Amsterdam, Boston PB - Elsevier/AP, Academic Press, is an imprint of Elsevier KW - Química bioorganica KW - QUIMICA FARMACEUTICA KW - Farmacología molecular N1 - Incluye índice; Incluye referencias bibliográficas; Introduction -- Lead discovery and lead modification -- Receptors -- Enzymes -- Enzyme inhibition and inactivation -- Dna-interactive agents -- Drug resistance and drug synergism -- Drug metabolism -- Prodrugs and drug delivery systems ER -